Apocynin, a Selective NADPH Oxidase (Nox2) Inhibitor, Ameliorates Behavioural and Learning Deficits in the Fragile X Syndrome Mouse Model
Background/Objectives: Fragile X Syndrome (FXS) Oven Control Knob is associated with intellectual disability, hyperactivity, social anxiety and signs of autism.Hyperactivation of NADPH oxidase has been previously described in the brain of the male Fmr1-KO mouse.This work aims to demonstrate the efficacy of Apocynin, a specific NADPH oxidase inhibit